User blog comment:MarvelFan2012/Questions and Answers about Spider-Man/@comment-3127363-20120729195438

I've always had a question, according to the various Spider-Man comic book titles around the time where the Queen Ana and Ezequiel first appeared, Spidey is actually some kind of mutant or natural born Spider powered creature. has this ever been confirmed, or did Spidey receive his powers entirely from the Spider bite, or how does that work?

I would appreciate if you could help ease my curiosity. Thanks