Thread:ADour/@comment-5679696-20160922231607/@comment-4651179-20160922234436

Unfortunately, I can't really give an opinion on this matter as I haven't read Runaways.

The article for the first issue of the Civil War mini-series lists Runaways #21, so it would seem the mini-series takes place between #21 and #22.

I think it's possible the note regarding #18 simply means the mini-series takes place chronologically after #18, but not necessarily right after #18. Maybe there was some important development in issue #18 that warrants being noted in the notes section of the mini's first issue?