User blog comment:MarvelFan2012/Questions and Answers about Spider-Man/@comment-5347501-20120730021111/@comment-5111260-20120801162144

They never saw the baby again. And plus, since Mephisto erased their marriage from existence, everything was changed so that Peter never married nor conceived a child with Mary Jane.

But in an alternate universe, Peter and Mary Jane are reunited with their baby by Peter's clone, Kaine, who rescued the baby from Alison Mongraine. Overtime, their baby grows up into a teenager named May "Mayday" Parker, whom becomes a hero called Spider-Girl since she inherited her powers from Peter.