Board Thread:General Discussion/@comment-7823447-20140508223520/@comment-24901406-20140525195459

Marc Webb has said he is interested in Kraven primarily and also Mysterio. Given Andrew Garfield is rumoured to have been signed up to make an appearance in The Sinister Six, I wouldn't expect the team itself to show up as the main villains of the third film, maybe just some more setting up (maybe even its formation).