User blog comment:Eal1545/Does Anti-Venom Know Who Spider-Man Is?/@comment-2096547-20110627034732

Anti-Venom doesn't know Spidey's identity. He currently has somewhat of a friendly rivalry with him, though he actually recently teamed up with Spidey against Mr. Negative. It can be assumed that the symbiote's "memory" was wiped as well as everyone else's due to OMD.

As for Deadpool, if he does know Spidey;s identity, then it is due to his fourth wall stuff. Deadpool can know everything pretty much. I wouldn't read much into him knowing Spidey's identity. It matters not.