User blog comment:Johnnybravo44/Comicvine makes me laugh/@comment-61371-20101125005855

Actually, I think the basis for Spider-Man being a "mutant" has its origins in the Earth X series, where it was theorized that EVERYONE who had super-powers was actually a latent mutant whose powers had been activated by some outside influence (Spider-Man's spider bite, the Fantastic Four and cosmic rays, the Hulk and gamma rays, etc.), I think that idea just kind of stuck around and people started thinking it was true of the mainstream Spider-Man. All kinds of misconceptions that get started this way and tend to stick and stick hard.

People assume Vertigo's a mutant because the rest of the Marauders are. Deadpool's so tied to the x-universe that it's just assumed. Same with Longshot, Sauron, Mimic, Spiral, Puck and Mr. Sinister. Juggernaut and Lady Deathstrike are similar, but can largely have their "mutant" status blamed on the X-Men movies. Cloak and Dagger are mutants every other week, so you've always got a 50/50 chance with them. Purple Man's daughter's a mutant, so combine that with his purple skin and people just make assumptions. Profile's entry in actually hinted at the possibility of him being a mutant. Plus, people STILL assume any new character without a specified origin must be a mutant. Hard habit to break people of, when, for so long, it was the accepted default.

Fenris and Living Monolith however...I thought they WERE mutants. ...So hard to keep some of them in line.