User blog comment:M(G)P/Alternate Universe Challenge No 2/@comment-1895174-20130127203820

Option #1:
 * Norman Osborn gave Dr. Octavius, his lead scientist, the task of developing a cure for HIV. Octavius believed the answer lied in spider venom.  The mad scientist genetically manipulated his test spiders to produce a large amount of a potent venom that had anti-viral properties.  One day, one of these spiders became a person.

Option #2:
 * Brundlespider