User blog comment:Edward Zachary Sunrose/Gwenpool Is Coming To Marvel Future Fight!/@comment-4548390-20160724070330/@comment-1894786-20160724231904

His status as a mutant is iffy. He claims to be one, but when House of M's Mister Sinister confirmed it, he said he wasn't a mutant. And then Rocket Raccoon confirmed Deadpool was a mutant with one of his gadgets. Deadpool's genetic make-up is as disputed as Cloak and Dagger's.

Either way, he's wrapped up in the Fox rights, and he's a mutant in that universe, so it's probably unofficially official that he's a mutant, since the comics do like to take traits from the movies sometimes.