Board Thread:General Discussion/@comment-10905624-20130819185428/@comment-61022-20130904220427

You see, before the Marvel NOW! reboot, Sam and Wade were really alternate reality brothers who travelled to Earth-616 to own a pony. Unfortunately, at the end of the Age of Ultron event the combination of the Multiverse has changed their origins and the writers have yet to figure out how to explain how they can't be brothers when they've been in the same universe the WHOLE time.

(But then again, I could have been mixing methamphetamines with DC Comics continuity again, so don't ask me for sources)