Board Thread:General Discussion/@comment-7823447-20140318205310/@comment-4651179-20140322035939

That was actually a Carbonadium blade. Carbonadium slows down healing factors (which would include Deadpool's). It's also worth to mention that one of the reasons Deadpool managed to kill Wolverine with some 4th wall wreckage.

The Muramasa Blade also slows down healing factors, and is even helluvah lot more effective than Carbonadium.