User blog comment:Artemis Thorson/Amazing Spider Man 2 Info/@comment-1895174-20121104163115/@comment-1713281-20121105082514

Well how interesting can you get with Green Goblin and Venom off limits from the first series? And by extension, people like Hobgoblin and the various symbiote villians are off-limits as well. Doc Ock and Sandman are out as well, and the Kingpin is still tied up by Fox in the Daredevil stuff. That leaves things like Shocker (Electro's brother in a padded suit), Hydro-Man (Sandman's blue brother), Mysterio (only good if you do a really good job at making the illusions dark and creepy, which would then draw comparison to Scarecrow in Batman Begins), Rhino (The Lizard with a horn), Vulture and Scorpion (both could be good, both could also be bad), Kraven (I can already hear the PETA protests), and Black Cat (SEX APPEAL!!!). Everything outside of that is a nobody to non-comic fans.

Then again, it'd be hilarious to see a fight between Spider-Man and the unlikely trio of Grizzly, Cyclone and Hammerhead