Just trap him in a vat of highly acidic acid and if he tries to escape, blast him with beams from a Laser Gun that is infused with cancer curing plants and elements of that skin curing soap that one smart kid made. Make sure it could also freeze people in place so you could put him back in the vat. Make sure that if it is a version of Deadpool that is scared of cows, put pictures of cows staring at him all around the vat, or you could just put other pictures of whatever else he fears around the vat if it is something scarier than a cow. Maybe also make sure he is dissected before you put him in the vat.