These are a set of three colored placebo pills used by Sgt. Frank Simpson, codenamed Nuke.[3] Each color of pill allegedly generated a different effect. Red pills supposedly increased his adrenaline, white pills ceased the previous pill's effects, and the blue pills relaxed him.[4] The fact that the pills are placebos suggests that Nuke lives in a constant state of increased adrenaline, but doesn't know it. The pills, therefore, trigger his violent behavior, but the effect is purely psychological.[3] However, the Santo Marcan Armed Forces created a plant where they manufactured red pills, which caused bursts of blind violence to the Nuke Platoon.[1]
Will Simpson was part of a private government project experimenting on soldiers. After being injured by Kilgrave, he called for the doctor of the project who gave him combat enhancers to speed up his recovery.[5] Overuse of the red pill caused Will to become overly aggressive and irrational.[6] When his dosage was at an abnormally high level, his ability to ignore pain increased to a point where he did not even notice potentially debilitating injuries; meanwhile, Simpson suggested without the blue pill "your brain will forget to tell your lungs to breathe." True to his word, Trish lost consciousness and fell into shock shortly after taking a red stimulant.[2]
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