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Tired of her husband, Tess decided to take control and have herself and her children, Sadie and Billy move out of Carrington Cottage, Colorado.[1]

During an argument with her husband regarding this, a strange dog entered the house and briefly watched the argument before a mysterious influence caused the dog's symbiote, Hybrid to split into four and begin violently bonding to the family. Tess herself ultimately fell victim to the Agony symbiote.[1]

The family, with new purpose, drove to New York[1], and were made hunt down Normie Osborn for his codex. Tracking him to Rex Strickland's warehouse in Manhattan, the symbiotes encountered resistance from The Maker, but Agony managed to burn through his weapons with her acid breath. However, Maker was able to detach them from the symbiotes and kept them in his test tubes.[2]

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