Alistair Smythe was a humanoid cyborg who worked for the Kingpin, who was working with Spider-Carnage to take over the world by controlling people's minds. Kingpin had suspicions and ordered Smythe to further analyze the machine. The plot was foiled by Spider-Men from different realities. Alistair was webbed up and sent spinning round and round in a robotic chair by one of the Spider-Men.
It later turned out that Spider-Carnage's real intention was to wipe out all of reality but he was stopped by the Spider-Men.
- The character was voiced by Maxwell Caulfield in Spider-Man: The Animated Series.