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Cancer was one of the several members of Vernon Jacobs' incarnation of the Zodiac.

When Pisces stole Peter Parker's personal Webware, which possessed special privileges and access to restricted data caches from his company Parker Industries, the device was taken to Aquarius' base to have its data decrypted by Cancer.

Spider-Man and the Prowler infiltrated the base and tried to get back the device before its data could be analyzed. When they were detected, Aquarius sent the data, still encrypted, to every Zodiac base and activated the base's self-destruct failsafe.[1]



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