The life of electronics expert Carlo Zota before he joined the Scientists Guild is unknown. In 1939, Zota, along with fellow Guild members Jerome Hamilton and Maris Morlak was present for the public debut of Professor Horton's android Human Torch.
In 1940, the Guild operated as a team of scientific adventurers called Three X. Each member used an alias, with Zota's being 2X. Zota was known as "a walking encyclopedia" for his vast knowledge. The Three X's visited private investigator Leslie Lenrow (a.k.a. the Ferret) and obtained the Eternity Mask, which they used the following year to empower Jerry Carstairs and turn him into the Thunderer.
Zota and his comrades met geneticist Wladyslav Shinski and the four of them eventually formed the Enclave, a new organization dedicated to the creation of life itself in hopes of creating a better Earth. Through the Enclave, Zota was directly involved in the creation of the artificial super-beings Adam Warlock and Ayesha.
Carlo Zota possesses the normal human strength of a youthful man his height, and build who engaged in moderate regular exercise.
- 17 Appearances of Carlo Zota (Earth-616)
- 3 Minor Appearances of Carlo Zota (Earth-616)
- Media Carlo Zota (Earth-616) was Mentioned in
- 9 Images featuring Carlo Zota (Earth-616)
- Quotations by or about Carlo Zota (Earth-616)
- Character Gallery: Carlo Zota (Earth-616)
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