The Carnage symbiote had been bonded to Aunt May. After she along with her husband, nephew, and Miles Morales discovered the Multiverse, they saw that there was no free will, since new universes were being splited by the different actions people did. They decided to go and murder all of their alternate counterparts, and eventually battled Spider-Ma'am, her husband and nephew, and Miles of Earth-1610. The villains were all defeated when Spider-Ma'am and Miles opened a portal which sucked the villains into another universe. However, Peter of Earth-3123 had gotten a piece of the symbiote from Carnage and was later seen studying it.