Ms. Marvel was one of the many superheroes that gathered themselves at the Baxter Building following the disappearance of fifty-two precent of Earth's population, which was caused by Thanos and his Infinity Gauntlet. The comsic monitoring equipment of the Fantastic Four, pinpointed a huge surge of activity only a few lightyears away from the galactic center of the Milky Way. Ms. Marvel was appointed as teamleader of the squad, that was sent in to investiagte. Her team consisted of Spider-Man, Hulk, Wolverine and Doctor Doom. They would be transported by Ulysses Archer and his Star Rig.
On their trip through hyperspace, they encountered Skrulls and Kree and stopped at space gas station, which was ambushed by Baron von Zeppelin and his zeppelin. They further clashed with a group of astrocrows.. Following a prolonged battle with Thanos, Spider-Man managed to get a hold of the gauntlet and used to return things to the way they were before.