The older sister of Morris Walters, she was deeply jealous of her brother for being their father's "favorite". Years later, she would use her own son David as an instrument of revenge, giving him injections that mutated him into into a super-strong, misshapen thug. She had David attack his uncle and cousin Jennifer (She-Hulk), intending for him to kill them. Her plans were set back when David refused to kill, recognizing it as "revenge", rather then the "justice" as she had always told him it was. The pair fled the scene soon after.
Very knowledgeable in science, especially in biology
Recipient of the Nobel Prize for Biology.
- 2 Appearances of Cassandra Pike (Earth-616)
- Minor Appearances of Cassandra Pike (Earth-616)
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- 1 Images featuring Cassandra Pike (Earth-616)
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