Death was present when Thanos gained all the Infinity Gems and activated the Infinity Gauntlet, killing half of all life in the universe to appease her. When Thanos was then attacked and easily defeat the universe's cosmic entities as the Four returned, Wolverine decided to team up with Thanos, replacing Mephisto as Thanos' advisor. The Fantastic Four changed their strategy in taking a Celestial armor, which was then implemented and controlled by Iron Man to attack Thanos. This, however, didn't work. As Thanos shielded himself, Wolverine asked him if he has ever touched Death as a part of love. After defeating Iron Man, Thanos was strongly convinced of Wolverine's suggestion and used the Gauntlet to touch Death. Just as he did this, Wolverine cut off Thanos' arm with the Gauntlet and left him to be physically assaulted by the Hulk. Spider-Man then utilized the Gauntlet and successfully restored the damages done by Thanos.