After infiltrating the S.H.I.E.L.D. network through a Trojan Horse malware virus program in Jessie Clatterbuck, Dimitrios was able to gain control of all of S.H.I.E.L.D.'s armada including their nano-fleet. Using the nano-fleet, Dimitrios attack individual and targets around the world and throwing the world into panic over the "nano-menace'. Next Dimitrios manufactured and distributed nano-disruptive rings, which also sterilized 98% of the human population.
On the eve of Dimitrios final siege of the Golden Knot, the Avengers Empire prepared to stop him, no matter the cost. Victor died in the initial assault, and Doombot sacrificed himself by activating the Black Hole in his chest plate. Unfortunately, Dimitrios was successful in riding Galactus' severed head into the Golden Knot along with Captain Alexis, who had been pulled in while attempting to prevent Dimitrios' entrance. Once inside the Golden Knot, their universe was destroyed, and they were greeted by the Bald Parrot.
- Because the Mjolnir he wields is from an alternate universe, Dimitrios does not need to be worthy to wield it.
- 2 Appearances of Dimitrios (Earth-14161)
- Minor Appearances of Dimitrios (Earth-14161)
- Media Dimitrios (Earth-14161) was Mentioned in
- 2 Images featuring Dimitrios (Earth-14161)
- Quotations by or about Dimitrios (Earth-14161)
- Character Gallery: Dimitrios (Earth-14161)
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