The home of the Totem Hunters and the Master Weaver. Earth-001 also contains the Web of Life and Destiny, which serves as a map of the Multiverse and is maintained by the arachnid deities known as the Spider-Totems.
- While it is possible that Earth-001 and Earth-1 are the same reality, it is also high unlikely, as the latter existed prior to the former's redesignation, and if they were intended to be the same, then the former would simply have been reassigned the exact same number, but instead was provided a deliberate difference.
- This reality was originally referred to as "Earth-000" in its first appearance in Superior Spider-Man #33. Further appearances corrected the numeration to "Earth-001."
- 36 appearance(s) of Earth-001
- 5 minor appearance(s) of Earth-001
- 8 mention(s) of Earth-001
- 141 image(s) of Earth-001
- 35 characters that originate from Earth-001
- 3 teams that originate from Earth-001
- 1 locations that originate from Earth-001
- 2 items that originate from Earth-001