Early in the 21st Century Sharzhad caused an alien energy to completly engulf the planet, which led to everyone not a mutant becoming infertile and everyone had to start being cloned to "reproduce". Large metro areas slowly transformed into Mondo Cities which became armed with people known as Bosses, who were the cities law enforcement who were made up of the genetic material of the Avengers. Approximatly 78 years after the energy wave, the Thunderbolts from the Prime Marvel Universe arrived into this future and met Boss Cage and the Outsiders.
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