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Unlike his Earth-616 counterpart, Peter Parker was allergic to the bite of the radioactive spider. He was sent into the hospital, where he was in a coma, and had his arm partially mutated.

Because of this, his Uncle Ben and Aunt May were accompanying him all day and night, and when their house was burgled, no one was murdered.

Spider-Man (Otto Octavius) sent Spider-Man Noir and a Six-Armed Spider-Man to recruit the spider-totem of this universe but they found Peter, of no use, in the hospital. Because he still had spider essence in his body, the Inheritors would come for him. The Six-Armed Spider-Man infiltrated into the hospital's laboratory and created a cure similar to the one which had given him his extra arms in order to cure the comatose Peter from his spider-blood so he would no longer be a target.

As the antidote was being developed, the comatose Peter turned into a mindless Man-Spider, which almost attacked his uncle and aunt if it wasn't for the intervention of Spider-Man Noir, who held him long enough for the Six-Armed Spider-Man to come back and inject him the serum and revert him to his human form.

The Spider-Men left Peter in the roof of the hospital, and he woke up shortly after being found.[1]

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