History
The Fantastic Four's history is presumably similar to their Earth-616 counterparts'. They once a Giganto unleashed by Namor and defeated it when the Thing detonated an atomic bomb inside it.[1] The team was likely wiped out when nuclear war devastated Earth.[2]
During the confrontation between the Hulk and the Maestro, the Maestro teased the Hulk by telling him that his presence at the time indicated the lack of vision on the part of his opponents by looking for him as his opponent, instead of people like Thor who could have opposed with his strength, or even better the Fantastic Four with the genius of Reed Richards at their helm.[3]