History
Karim Mahwash Najeeb disappeared soon after visiting the Hu Po Psychiatric Institute.[1]
He and Darius Faraz freed the Mandarin from his cell.[2]
Darius then merged the Mandarin's Rings into his master's spinal cortex.[3]
When Iron Man and the S.H.I.E.L.D. Alpha Team broke into the institute, they were infected by a genetically engineered neoplastic tumor.[4]