Lou was one of the many robot duplicates of the Tarleton family created by Arcade, placed alongside a fellow robot duplicate and a real family robot. The three were forced to watch M.O.D.O.K. interact with the robot duplicates, making unsuccessful attempts to contact him until M.O.D.O.K. himself was revealed to be a robot built by the real M.O.D.O.K. The robot M.O.D.O.K. self-destructed as the three were freed from their restraints by M.O.D.O.K.'s hacking skills. Jodie, Melissa and Lou then met in Murderworld with M.O.D.O.K., two other versions of the family and their captors. Arcade explained the nature of Murderworld's death game, each torture chamber had one real family member and two robots and the true versions of the family needing to kill the robot duplicates to escape; Arcade then disorientated the families so they couldn't tell who they came in with and introduced two robotic duplicates of M.O.D.O.K. Eventually, the family was able to eliminate most of the robot duplicates, with the robots either being killed by the real versions, committing suicide or accidentally killing themselves. Lou and his human counterpart were the only uncertainty left, however, due to Lou's affable nature the family decided to kill neither Lou. M.O.D.O.K. goaded the Anomaly into a fight, causing Arcade to leave in protest. The Anomaly ripped out a vital piece of circuitry from M.O.D.O.K., making Jodie retaliate and rip the Anomaly in half. Melissa was able to save M.O.D.O.K's life by re-attaching the piece of circuitry. The family, went to dinner together. There, the Super Adaptoid came and apologised for betraying the family, causing them to reset him. The two Lous continued their life, with no way of telling which was which. . The two Lous agreed to share the same amount of food as one Lou, making the Tarleton grocery budget unchanged. 
Both Lous took part in their Bar Mitzvah, fully indulging in their eccentrics and theatrics during the Torah reading. Upon the reception, M.O.D.O.K. was not able to gain many teenage guests due to a misunderstanding, instead bringing patrons from the Bar with No Name, Ciegrimites and Jiggle-Os. The two Lous were miserable during their Bar Mitzvah, causing M.O.D.O.K. to talk to them. The Two Lous explained that they felt ignored by M.O.D.O.K. The two Lous danced with their father until they eventually broke off as the Lous begun socialising with Carmilla. After the Super Adaptoid freed two Ciegrimites from their restraints, the Anomaly arrived, the version Jodie had killed having been a robot duplicate, and fired missiles at both Lous and the rest of M.O.D.O.K.'s family. Killing them in an attempt to make his Earth-1226 Counterpart fulfill his dream of ruling the earth. 
Upon taking over the Earth, M.O.D.O.K. vowed to save Lou and the rest of his family and bring them to his utopia. 
Lou's personality was exactly the same as his human counterpart. The two Lous were friends with each other.
Powers and Abilities
- Magic tricks
- Voiced by Ben Schwartz.
- 2 appearance(s) of Louis Tarleton (Robot Duplicate) (Earth-1226)
- 1 minor appearance(s) of Louis Tarleton (Robot Duplicate) (Earth-1226)
- 1 image(s) of Louis Tarleton (Robot Duplicate) (Earth-1226)