A bunch of Neanderthals were shown living on an island in the Savage Land's inland sea. They ended up in a fight with Wolverine (who was trying to save the S.H.I.E.L.D. Agent that they captured) until Shanna the She-Devil arrives. While setting out to destroy the Cthulhu-type machine, Wolverine and Shanna the She-Devil encounter heavy Neanderthal resistance. During the fight against the Neanderthals, Shanna was killed by one of them, leaving Wolverine alone. Luckily for Wolverine, Amadeus Cho was also on the island and convinced the Neanderthals that he was their god and to help Shanna by using the life blood of a Man-Thing native to the Savage Land to resurrect her.
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