When a plague turned the world's population into cannibals, Moon Knight helped hold back the infected. The science team working to find a cure needed to be moved out of New York City, so he and many other heroes acted as decoys on the Goethals Bridge to distract the infected. However, they did not expect a confrontation with the Hulk's tribe. Though many died on both sides, Moon Knight survived.
Eventually Doctor Doom offered a cure to the Avengers in exchange for being named Emperor of Earth. Despite their reluctance, they agreed to his terms. Moon Knight, along with almost every person in New York City, wore one of Doctor Doom's Doomstones, his proposed cure. However, the Doomstones were actually a means for Doom to turn its wearer into a cannibal, and Moon Knight succumbed shortly after they were activated.
Due to his exposure to Survivor 118, Moon Knight was capable of adapting to extreme changes.
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