- Doctor Doom (Victor von Doom)
- The Cabal
- J. Jonah Jameson (Appears on a computer screen, TV, or hologram only)
- Spider-Man (Peter Parker) (Mentioned)
- Doctor Doom's Armor
- Iron Man Armor MK L
- Falcon Armor
- Hawkeye's Bow
- Captain America's Shield
- Trick Arrows
- Iron Skull Armor
A newscast by J. Jonah Jameson informs the city of Doctor Doom coming to speak before the United Nations. Doom refused membership to the Cabal so now the Red Skull wants him dead. S.H.I.E.L.D. has assigned the Avengers to be his bodyguards as Doom speaks to the UN. The team is there with Fury, he says that Doom only has diplomatic immunity so long as he does nothing wrong. Shortly after Doom begins his address, The Cabal, in the form of Hyperion and MODOK controlling the Super-Adaptoid, attack. Hyperion tears through the Avengers like they’re nothing.As Captain America tries to smuggle the wounded and helpless Doom to safety, more of The Cabal attacks, in the form of Dracula and Attuma. Thor and Hawkeye step up to fight the good fight. When the Red Skull shows up and takes down Captain America, Doom and the Skull fight in public. But later it reveals he wants access to the tower so he can access to the Avengers and SHIELD’s files. Cap and Stark let him download a virus instead before he escapes.
- During his opening broadcast, J. Jonah Jameson takes the time to make a rip at Spider-Man's expense, referencing his long-running smear campaign against him in the hero's own series.
- As ruler of Latveria, Doctor Doom has Diplomatic immunity. He loses his immunity as a consequence of fleeing the country with stolen property from Tony Stark.