Appearances
Featured Characters:
- Super Hero Squad
- Hulk (Bruce Banner)
- Bucky (Exclusive to PlayStation 3 and Xbox 360)
- Wolverine (James Howlett)
- Reptil (Humberto Lopez)
- Quicksilver (Pietro Maximoff)
- Scarlet Witch (Wanda Maximoff)
- Thor Odinson
- Spider-Man (Peter Parker)
- Silver Surfer (Norrin Radd)
- Nova (Richard Rider)
- Captain America (Steven Rogers) (Exclusive to PlayStation 3 and Xbox 360)
- Black Widow (Natalia Romanova) (First full appearance)
- Iron Man (Tony Stark)
- Invisible Woman (Susan Storm)
- She-Hulk (Jennifer Walters)
- Falcon (Samuel Wilson)
Supporting Characters:
Antagonists:
- Annihilus
- Dark Surfer (Norrin Radd)
- Galactus
- Grandmaster (En Dwi Gast)
- Hercules
- Loki
- Magneto (Erik Lehnsherr)
- Nebula
- Nightmare (First appearance)
- Red Skull (Johann Shmidt) (Exclusive to PlayStation 3 and Xbox 360)
- Super-Skrull (Kl'rt)
- Thanos
- Lethal Legion
Other Characters:
Locations:
Items:
- Infinity Gems
- Mjolnir
- Spider-Man's Web-Shooters
- Silver Surfer's Surfboard
- Captain America's Shield
- Black Widow's Gauntlets
- Iron Man Armor
- Falcon's Wings
Vehicles: