This looks like a job for... The Merc with only a Mouth! No guns! No healing factor! No limbs! NO PROBLEM!!! 
Appearing in "Midnight Sons, part 1"
Featured Characters:
Supporting Characters:
- Simon Garth: Zombie
- Zombie Deadpool (Just a head)
Villains:
- Zombie Men-Fish
- Zombie Piranha
- Black Talon (Desmond Drew)
- The Hood (Parker Robbins)
- The Hood's Gang
- Crimson Cowl (Justine Hammer) (Cameo)
- Brothers Grimm (Percy & Barton Grimes) (Cameo)
- Bulldozer (Henry Camp) (Cameo)
Other Characters:
- Zombified Morbius (Only in flashback)
- Captain Mexica (Only in flashback)
- Zombified Tainians
- "Survivors" of the Tranquility Cruise
Locations:
- Earth-616 (Reality)
- A.R.M.O.R. Headquarters
- Caribbean Sea
- The S.S. Tranquility, two days out of San Juan
- Taino
- Black Talon's Plantation
Items:
- Pneumatic rifles, canisters with oxidizing bacteria
- Amulets of Damballah
Vehicles:
- S.S. Tranquility, a Royal Swedish cruise liner
Synopsis for "Midnight Sons, part 1"
Simon Garth escaped A.R.M.O.R.'s HQ along with Zombie Deadpool's head. They teleported to the bottom of the sea, where they met the Men-Fish, and spread the Zombie contagion to them. The Men-Fish attacked the S. S. Tranquility, killing most of the crew, and the new team, The Midnight Sons, were called in to track the virus and cure it. While they deal with a zombified Piranha, Garth and Wilson continue on their way, meeting up with Black Talon, who immediately sees the zombie virus as a marketable weapon to deal to some of his criminal friends, namely, The Hood.
Notes
The Last Defenders later return in Vengeance #1