They became closer and their relationship became deeper until eventually, she agreed to marry him. Overjoyed, Otto told his mother, who responded by being very angered that her son would abandon her like that after she raised him. His mother influenced Otto to break off his engagement, breaking both his own, and Mary Alice's hearts. Mary Alice would later die from an HIV infection, despite Doc Ock's attempts to synthesize a cure.
It was later revealed that Norman Osborn was the one who was responsible for infecting Mary with HIV. He had her run off the road, and then infected her with a blood transfusion, in an attempt to desensitize Doc Ock.
- 9 Appearances of Mary Alice Anders (Earth-616)
- 2 Minor Appearances of Mary Alice Anders (Earth-616)
- Media Mary Alice Anders (Earth-616) was Mentioned in
- 3 Images featuring Mary Alice Anders (Earth-616)
- Quotations by or about Mary Alice Anders (Earth-616)
- Character Gallery: Mary Alice Anders (Earth-616)
- Dr. Mary Alice Burke on Appendix
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