Mephisto was the ruler of one of twelve planets with sentient life on it. He would spread the forces of Anti-life and disease across the Universe. He quickly found the Skrulls and molded them into violent and hateful warriors to destroy civilizations and planets. The Skrulls tapped into the substance of Mephisto's world to create the anti-life virus called Galactus, which then went on to devour the life forces of many worlds.

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