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Black Widow shared a similar history to her Marvel Cinematic Universe counter-part until after the Chitauri invasion of New York City. During Tony Stark's birthday party a Zombie attacks but was taken out by Black Widow. However, it was discovered that the infection is spread by touch and both Thor and Black Widow have become infected. They attempted to contain Thor and Black Widow whilst Bruce Banner and Tony looked for a cure. Thor escaped and went after the other Avengers.[1]

Bruce eventually able to to develop a new anti-virus was able to administer it to Thor, Black Widow and Toshiko before he was himself infected and turned into a zombie Hulk. Iron Man, Cap and Hawkeye awoke to find themselves uninfected having been saved by a Dr. Jasper Scott, who had administered a "cure" to each of them.[2]

The three of them tried to stop Hulk, but were unable to until a newly cured Thor and Black Widow administered the cure to Hulk, reverting him back to normal. Toshiko arrived and it was discovered the Dr Jasper Scott had infected Iron Man, Cap and Hawkeye with a new strain of the virus that was not responding to the current anti-virus and she revealed he was her brother and the actual source of the virus. Whilst they had been working on an early stage of it, they discovered it could regenerate missing fingers and Jasper was patient zero. Jasper, meanwhile was unleashing his new zombies onto New York.[3]

The Avengers went out to Jasper and were overwhelmed by the zombies long enough for Jasper to kidnap Bruce and attempted to use him to convince Tony to return to weapon's manufacturing. Bruce refused and was eventually rescued just before it was revealed that Jasper was mutating into a Human-Chitauri hybrid.[4]

They were able to defeat him and Bruce administered a cure he had obtained from Jasper on the remaining Zombies and when Thor left he took all samples of the virus and any data on it to Asgard.[5]

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