The past history of Mr. Sinister of Earth-21993 mostly mirrors that of his Earth-616 counterpart. In this reality Charles Xavier would be assassinated by Cable leading to widespread human/mutant violence.

In the power vacuum caused by Xavier's death, Mr. Sinister would order his Nasty Boys to collect the heads of Roxxon Oil, the P.T.L. Group, and the Boy Scouts of America, seeking to put them under his influence[1]. The outcome of this plot remains unrevealed.

Mr. Sinister and his Nasty Boys would come afoul of Wolverine's X-Men who, after killing Cable in retribution of his assassination of Xavier, would be seeking to eliminate other X-Men foes. Mr. Sinister would be slashed to death by Wolverine[2].

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