As opposed to most cross-species experiments, which were usually the result of one scientist in his lab, this piranha infused with human DNA was the product of a team of Oscorp scientists working from Curt Connors’ research. Though only loosely associated with the group, Dr. Mendel Stromm took to calling this experiment "Nattie", based on the subject’s scientific name, Pygocentrus nattereri. Stromm's colleagues found great humor in the contrast of such a nonthreatening name belonging to one of the most ferocious fish on Earth, and the moniker caught on.

Beyond Nattie's odd name, the beast's story is about as straightforward as it gets. No one even bothered to record the identity of the human donor, so it is impossible to observe whether or not Nattie has taken on any of his "father's" traits.

All signs point to Nattie's human half coming from a fighter, as he's surprisingly brutal on land, where his charge attack is second only to Rhino's. He can even follow this up with a deafening scream capable of knocking even Spider-Man off his feet. And when Nattie confronts his prey under water, his victim doesn't stand a chance…


Nattie broke out of containment at the same time as all the other cross-species creatures, but Nattie himself appeared to stick to the sewers, where there was a source of water.

Nattie (Earth-TRN376) and Peter Parker (Earth-TRN376) from The Amazing Spider-Man (2012 video game) 001

Nattie attacking Spider-Man in the sewers

Nattie encountered Spider-Man during his hunt for The Lizard and attacked him. Spider-Man was able to drain the water in the area, which removed Nattie's advantage in the fight. Nattie managed to summon a small group of other fish-like cross-species, possibly civilians infected with the cross-species virus, but this proved to be no help. Spider-Man defeated all the cross-species in the sewer, including Nattie, and continued his search for The Lizard.[1]


Kraven the Hunter was hired by OsCorp was hired to kill Nattie. He was successful, and he stuffed and mounted Nattie as a trophy.[2]

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