The Neo-Sentinels are a new design inspired by Bolivar Trask's original Sentinels.
On Earth-616, the Neo-Sentinels were created by Bolivar Trask's son Larry, destined to be used as trackers and hunters against the mutant menace, in order to avenge his father that he erroneously thought to have been killed by the X-Men.
In the same way on Earth-161, Bolivar' daughter Ziggy Trask followed Bolivar's dream, in order to avenge him and Larry, both to have died in encounters between X-Men and Sentinels (as in -616), but also her grandfather Dietrich Trask, a Nazi scientist killed by Logan during WWII, as he was creating a genetic data detectors.