A female Skrull alien named De'Lila who was an empath, a shape-shifter, and a telepath managed to capture the true Fantastic Four. Pretending to be Susan Richards she convinced Wolverine, Spider-Man, Hulk, and Ghost Rider to form a New Fantastic Four to avenge their "deaths". She sent them to fight the Mole Man so that she could steal a powerful Skrull device that crash-landed on Monster Isle.
When Franklin and Valeria needed help while the FF were away dealing with the latest Kree-Skrull threat, Valeria activated an emergency signal that summoned Spider-Man and Wolverine to aid them, but a message from their father confirmed that the children should consider themselves members of the team as well.
- In story arc Circle of Four Venom teamups with X-23, Red Hulk and Alejandra Jones, making homage to New Fantastic Four.
- Another homage happens in Ghost Rider Vol 8, when Robbie Reyes teamups with Amadeus Cho, Laura Kinney and Cindy Moon
- 7 members of New Fantastic Four (Earth-616)
- 13 appearances of New Fantastic Four (Earth-616)
- 2 minor appearances of New Fantastic Four (Earth-616)
- 3 mentions of New Fantastic Four (Earth-616)
- 25 images of New Fantastic Four (Earth-616)
- Gallery of New Fantastic Four (Earth-616)