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Madame Hydra is the leader of Hydra. With the help of Dr. Dikau, she brainwashed the Avengers, making them believe that they were fighting the Hydra agents. Instead, they were destroying a base of SHIELD. After defeating their conditioning, the Avengers defeated Hydra, and the Black Widow defeated and captured Madame Hydra.[1]

Abilities

Seemingly those of the Ophelia Sarkissian of Earth-616.


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