Dr. Octopus was one of the many villains who helped Doctor Doom collect the Cosmic Bricks from the Silver Surfer's surfboard. He steals the one Brick Mr. Fantastic was studying at the Baxter Building. Mr. Fantastic, Captain America, and Spider-Man stopped Doc Ock after a fight in Times Square, but the Green Goblin swooped in on his Goblin Glider to take the Cosmic Brick back to Latveria. Doc Ock was later one of the villains who helped S.H.I.E.L.D. and the Avengers fight Loki and Galactus.
- Otto's constant use of the word superior is a reference to how his Earth-616 counterpart switched bodies with Spider-Man
- In the Maximum Overload series, Ock appeared in the likeness of his Earth-12041 counterpart. Probably because his regular look hadn't become a minifigure yet.
- 4 Appearances of Otto Octavius (Earth-13122)
- Minor Appearances of Otto Octavius (Earth-13122)
- Media Otto Octavius (Earth-13122) was Mentioned in
- 8 Images featuring Otto Octavius (Earth-13122)
- Quotations by or about Otto Octavius (Earth-13122)
- Character Gallery: Otto Octavius (Earth-13122)
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