Appearing in "In the Blood, Part One"
- Jaten (Death)
- 🢐 Jigsaw (Billy Russo) 🢒
- the Hood (Parker Robbins) (Mentioned)
- H.A.M.M.E.R. (Mentioned)
- Maria Castle
- Jigsaw (Stuart Clarke)
- Dormammu (Mentioned)
- Warden Jasta (Mentioned)
- S.H.I.E.L.D. (Mentioned)
- Lady Punisher (Lynn Michaels) (Mentioned)
Synopsis for "In the Blood, Part One"
Following the defeat of Norman Osborn, the Punisher has started hunting the Hood but without results, so he goes after his old partner Microchip to make him pay for murdering G.W. Bridge.
Meanwhile, Microchip is knocked unconscious by Jigsaw. At their hideout, Henry Russo tells the Punisher how he hated his father because he would constantly abuse his mother and idolized the Punisher for being a thorn in Jigsaw's side. Henry suspects that his father may be alive and despite the Punisher's protests, goes to visit his mother to make sure; however, when he arrives, he is confronted by his father Jigsaw and Stuart Clarke.
Meanwhile, the Punisher starts heading to Microchip's lair but instead of finding his old partner, he finds a mysterious woman in black leather with seemingly burnt skin who then attacks him. She called Frank in the story "Angel" and after she escaped, Frank suspected that he may know this woman very well.
Frank Castle is back. Back for revenge. Back in New York. Back to cleaning its streets. Back together, healed and strong, his mission resumed as he partakes in the sweet wet work, and notches up one of the highest body counts in Punisher history. Cyber sensei Henry Russo is back, keeping Frank proficient with an eye in the sky. Others are back as well – two of Frank’s most sadistic enemies united in a new vindictive plot: Enter the Jigsaw Bothers!
- This story is reprinted Punisher In the Blood and Punisher Rick Remender Omnibus.