After Rahne Sinclair's lycanthropy mutation manifested, she considered it a sin and turned to Reverend Craig for guidance. He asked Rahne to show it to him, and after witnessing her transformation, he nearly beat her to death and branded her a monster. Rahne eventually killed him, although Reverend Craig would continue to haunt her fears. Because of this, she ended up in the Milbury Hospital, where she met Roberto Da Costa, Sam Guthrie and Illyana Rasputin, fellow mutants with their own dark pasts. They collectively believed that they were being trained to become X-Men, hence the strict supervision. Meanwhile, Dr. Cecilia Reyes reminded them that they were considered dangerous and should not leave the Hospital until their powers were under control.
One day during a therapy session with Dr. Reyes they were joined by another fellow mutant Danielle Moonstar whose powers were unknown. When Danielle Moonstar arrived at Milbury Hospital, Rahne and her friends met her in the meeting room. After Illyana showed contempt for Dani and was forced by Dr. Reyes to show Dani the hospital sites, Rahne followed them in her wolf form. Later that day she stopped Dani from commiting suicide by jumping off the church's window. Rahne took a liking to Dani, showing her the ventilation shafts she used to move around the facility and taking her out during the night.
As days passed, the patients warmed up to each other and eventually the group came together when Illyana spikes Dr. Reyes' coffee with sleeping pills, allowing them to run amok on the grounds. While taking a showed, Rahne was shocked to find Reverend Craig coming back from the dead for her and branding her again, this time on the neck. The group soon discovered that Reyes had been lying to them and that the Essex Corporation planned on using them as mutant killers. They confronted Reyes, who trapped them inside force fields, but manifestation of Dani's mutant powers conjured the Demon Bear who killed Reyes and proceeded to hunt them. Rahne took Dani to safety and guided her in the spitit world until Dani got a hold of her powers and drove the Demon Bear away. As the sun rose, the New Mutants collected their belongings and Sam noticed that the force fields around the Hospital was no longer there. The group decided to head into the nearby town which Reyes had previously told them was twenty miles out. Not knowing whether she was telling the truth, they all decided to head out together; facing the unknown.