Ramon was the cousin of Glory Grant, a longtime friend and co-worker of Peter Parker. Ramon, along with a few other people, was drugged by the villain known as Midas the Golden Man, causing them to act violently. They were defeated and freed from their control by Spider-Man and the Falcon.
Later, Ramon was found by Spider-Man in a zombie-like state after an encounter with Haitian refugees during a cruise. This was later discovered to be part of a plot for Spider-Man's nemesis Calypso to resurrect herself. Calypso successfully resurrected herself, and Ramon presumably returned to normal.