Scream was one of the five Life Foundation Symbiotes that were forcefully spawned from the Venom symbiote.
Donna Diego was a mercenary hired by the Life Foundation. In order to fulfill her role as a superhuman officer for the corporation's future utopia, she was granted one of the 5 symbiotes forcibly spawned from the Venom symbiote.
Patricia Robertson was a twenty-four year-old lieutenant and communications specialist in the US Army who was bounded to a Venom symbiote's clone before it merged to Venom. Years later Patricia was overwhelmed and bonded to the Scream symbiote, and the two succumbing to the dark god Knull 's control.