The Life Foundation

Captured by the Life Foundation, the Venom symbiote was experimented upon and forced to give birth to five symbiotes which were bonded to mercenaries intended to act as super-soldiers. One of the five symbiotes, eventually codenamed "Scream," was bonded to Donna Diego, a mercenary suffering from schizophrenia.[1]

In an eventual confrontation with Spider-Man and Venom, her "father" released a metabolic accelerator on them, eventually making them die from aging.[2] However, thanks to the efforts of the Life Foundation, they survived. As the Scream symbiote and its siblings began attempting to compel their hosts to violence, Donna and the other mercenaries left the Life Foundation and searched for Eddie Brock, the host of the Venom symbiote, hoping he would help them control their symbiotes. Eddie, dismissing them as lost causes who would turn out as bad as Carnage, refused to aid them.[citation needed]

Diego asked the Scarlet Spider to help her find Brock, but he also refused. Succumbing to her schizophrenia and the Scream symbiote's bloodlust, Donna began rampaging through Times Square and was confronted by both Venom and the Scarlet Spider. Venom almost killed Scream, but was stopped by the Scarlet Spider.[3][4][5]

After Eddie was arrested and separated from the Venom symbiote, Scream and her "brothers" tried to help him recover his symbiote by taking him to Chicago. Succumbing to her psychosis, Scream killed the other mercenaries and tried to kill Eddie as well, but he defeated her after recovering the Venom symbiote.[6][7][8]

Regaining her hold on sanity, Donna began using the Scream symbiote to act as an antihero but found herself hunted by a Xenophage - a species of alien that ate symbiotes. Donna and the Scream symbiote were nearly eaten by it, but managed to defeat it with help from Venom.[9]

The Scream symbiote was ultimately killed alongside Donna by Eddie Brock, who incapacitated it with sonic feedback and stabbed her to death with a heated knife.[10]

Absolute Carnage

Years later, Scream was resurrected by Knull, still bonded to Donna's corpse. When Patricia Robertson - a soldier who had formerly hosted a clone of the Venom symbiote - attacked it, Scream abandoned Donna's skeleton and bonded to her. Initially having assimilated Donna's personality and mental voices, Scream succumbed to Knull's control and attacked Andi Benton, who it recognized its host bore a grudge against for having bonded to and lost the cloned symbiote.[11] Patricia's strong will helped the Scream symbiote resist Knull's control, but it succumbed again when attacked by Carnage.[12] Persuading the Scream symbiote to resist Knull's control a second time, Patricia sacrificed herself in an attempt to save Andi's life, and the Scream symbiote left her corpse and bonded to Andi.[13]

Unlike Andi's amicable relationship with her previous symbiote, she came to loathe being bonded to the Scream symbiote, trying to shut it out of her mind and demanding that it abandon her like everyone else had. Despite Andi lashing out at it in her despair and anger, the Scream symbiote protected her whenever she was attacked, and helped her in hunting would-be rapists. When Andi attempted to commit suicide, the Scream symbiote regained its voice and saved her, though their subsequent argument was interrupted when Andi was attacked by Lovecraftian monsters. Taking over, Scream noted that the creatures were formed from drowned corpses fused to sea life and reanimated by living abyss, and scornfully killed them before telling the traumatized Andi that it would keep her safe. Following Andi angrily telling it that it was endangering her, the Scream symbiote fell silent for several days, only breaking its silence to desperately beg Andi not to listen to a woman claiming to be her mother.[14]

The woman was revealed to be a corpse reanimated by a symbiote, which pursued Andi to the F.E.A.S.T. shelter and took over the homeless people staying there. Absorbing a piece of the symbiote, the Scream symbiote succumbed to Knull's control and killed the infected homeless people.[15] Realizing that it and Andi were being hunted by a powerful ancient symbiote, the Scream symbiote and Andi declared a truce to deal with the threat and descended to the bottom of Upper New York Bay. Attacked by Big Mother, the Scream symbiote rebuked the ancient symbiote's desire to claim it as her "child". Battling Big Mother, the Scream symbiote was separated from Andi twice, but managed to break free of Big Mother's clutches and save her. The Scream symbiote and Andi acknowledging each other as family and accepting their bond, Scream lynched and decapitated Big Mother, though the Scream symbiote warned Andi that Big Mother was not dead and would likely return to seek revenge.[16]


The Scream symbiote gives to its host the following powers:

  • Superhuman Strength
  • Superhuman Durability
  • Superhuman Stamina
  • Accelerated Healing Factor
  • Wall-Crawling
  • ESP (Spider-Sense)
  • Immunity to Spider-Man's Spider Sense
  • Webbing Generation
  • Camouflage Capabilities
  • Constituent-Matter Generation
  • Constituent-Matter Manipulation (Hair): Unlike her fellow symbiotes, Scream preferred to extend her hair-like tendrils to lash at or encircle her foes.


  • Heat and Sonics: Like most symbiotes, Scream is vulnerable to intense heat and sonic vibrations.

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