Quote1 We'll win. Don't you realize that? You humans... you're too weak. The Symbiotes are more powerful. Quote2
-- Scream src

Scream was bonded to Donna Diego.

Hoping to turn her into the new brood mother of the klyntar, Poison tricked Mayhem into bonding with Scream. Parker resisted this process multiple times and they gave up with bonding the two. Instead, Venom had his host, Eddie Brock, bond with Scream until she returned to full strength.

Scream was among the symbiotes imprisoned in the Symbiote Prison. He rejoined The Symbiotes to organize a prison break and extract revenge on Spider-Man.[1]


Seemingly those of the Scream of Earth-616.

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