They clashed with the Young Ultimates after they confronted the criminal Stone in their territory. They fought the Ultimates and a couple of NYPD detectives before fleeing upon the arrival of a SWAT quad.
Back in their HQ, the Serpents planned their next moves. As they attributed the deaths of their members caused by the Scourge to rival gangs, the Serpents began attacking other gangs all over New York City.
While King Cobra was selling drugs to Mister Jips, the transaction was interrupted by Spider-Man, who had followed Serpent Skulls member Poey and his girlfriend Lana, who was secretly the Ultimate Bombshell. During the fight, the Skulls' supply was destroyed.
Diamondback later broke into Poey's house and killed him, as it had been his fault the supply had been destroyed. When Lana arrived to Poey's house, Diamondback sprayed her a drug to be able to control her will, and planned to force Lana to take them to the hideout of the Young Ultimates.
- 7 Serpent Skulls (Earth-1610) Members
- 7 Appearances of Serpent Skulls (Earth-1610)
- Minor Appearances of Serpent Skulls (Earth-1610)
- 1 Media Serpent Skulls (Earth-1610) was Mentioned in
- 3 Images that include Serpent Skulls (Earth-1610)
- Organization Gallery: Serpent Skulls (Earth-1610)