Nathan was a young boy, who sadly was diagnosed with cancer. He was one of Spider-Man's biggest fans and his dream was to become the sidekick of Spider-Man. In order to make his wish come true, Spider-Man was contacted by the hospital. Spider-Man agreed to spent some time with Nathan and the two started playing together. They imagined that they were fighting "Sinister Sixty", comprised of most of Spider-Man villains. After defeating the man behind the formation of the group, "Stilt Man", the hospital staff and Nathan's parents interrupted the imagination as it was time for Nathan to go to sleep. However, Nathan refused to go to sleep as he was afraid that he would not wake up afterwards. Spider-Man decided to go swinging around the city with Nathan, in order to make him feel better and fulfill his dream. His fate afterwards remains unknown.
- Cancer: Nathan suffers from cancer.
- Nathan seems to be based on Batkid.
- Nathan's Spider-Bite costume is similar to that of the Spider-Man from the Ultimate Spider-Man animated series.
- 1 Appearances of Spider-Bite (Nathan) (Earth-616)
- Minor Appearances of Spider-Bite (Nathan) (Earth-616)
- Media Spider-Bite (Nathan) (Earth-616) was Mentioned in
- 3 Images featuring Spider-Bite (Nathan) (Earth-616)
- Quotations by or about Spider-Bite (Nathan) (Earth-616)
- Character Gallery: Spider-Bite (Nathan) (Earth-616)
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