| Spider-Boy |  Sure, Ock--just saved Manhattan and trashed a one-of-a-kind invention, that's all!  |
| Doctor Octavius | Ah! Again! |
Appearing in "Big Trouble"
Featured Characters:
- ⏴ Spider-Boy (Pete Ross) ⏵ (Main story and flashback) (First full appearance)
Supporting Characters:
- Betty Brant
- Challengers of the Fantastic
- Computo
- Insect Queen (Mary Jane Watson)
- Daily Bugle
- Project Cadmus
- Rex Leech
- Special Crimes Unit (First appearance)
- Brooklyn Barnes (First appearance)
- Flash Thompson
- Roxy Leech
- Sam Makoa
Antagonists:
- Bizarnage Symbiote (First appearance)
- King Lizard
- Victor von Doom
- Mugger (Only in flashback)
Other Characters:
- Bruce Wayne (Mentioned)
- Super-Soldier (Clark Kent) (Mentioned) (Only in flashback)
- Peter Parker (Only in flashback) (First appearance; dies)
- Thunderbolt Ross (Only in flashback) (First appearance; dies)
- Judgment League Avengers (Mentioned)
- Conan (Mentioned)
- Ka-Zar (Mentioned)
Locations:
Items:
- Spider-Boy's Gun (First appearance)
Synopsis for "Big Trouble"
- Synopsis not yet written