Appearing in ""Book four""
Featured Characters:
- Spider-Man (Peter Parker) (Main story and flashback)
Supporting Characters:
- J. Jonah Jameson (Last appearance)
- Mary Jane Watson (Only in flashback) (Last appearance; illusion)
- Aunt May (Last appearance; illusion)
- Uncle Ben (Last appearance; illusion)
Antagonists:
- Sinner Six (Disbands)
- Venom (Eddie Brock) (Death)
- Electro (Maxwell Dillon) (Death)
- Scorpion (Mac Gargan) (Death)
- Mysterio (Quentin Beck) (Death)
- Hydro-Man (Morris Bench) (First appearance; dies)
- Kraven the Hunter (Sergei Kravinoff) (Last appearance)
- Reign (Disbands)
- Sandman (William Baker) (Death)
Other Characters:
- Mayor Waters (Apparent death)
- Masked youths/Kids (Last appearance)
- Unknown girl (Susie Baker) (Death)
- Chris (First appearance)
Locations:
- Earth-70237
- Tower (Last appearance)
Items:
- The detonator from Sandman (Only appearance; explode)
- Web-Shooters
- Mary Jane Watson-Parker's tombstone
- Venom Symbiote (Death)
Synopsis for ""Book four""
Interior Panels
The unconverted population use bells to drive the symbiote invasion back, and Sandman decides to go back to the good side of the law when the Reign attacks and later kills his daughter, Susie, whom he had never met before.
Spider-Man defeats the remaining members of the Sinner Six and battles Venom, and it quickly looks like this will be his last fight. Sandman comes at the last minute, gives Peter a detonator telling him that the six of them were implanted with detonators that would explode if they ever disobeyed Waters' orders. Peter activates the detonator causing the Six to explode, and killing Venom in the process.
After Venom and the Reign are destroyed, Jameson reports that all crime levels are back where they were years ago, but heroes have grown at the same rate. Peter in silhouette visits Mary Jane's grave, he states that he will join her in peace one day, but until then, he has "responsibilities".