- Spider-Man's Suit
- Doctor Octopus' Tentacles
- Goblin Armor
- Pumpkin Bombs
- Mysterio Suit
- Vulture's Wings
Doctor Octopus is plotting the crowning caper of his criminal career... to rule the world! He has reunited the Sinister Six to reach his goal, and it appears nothing stands in the way of the super villains, except Spider-Man.
- The game is based on the Return of the Sinister Six story line found in Issues 334-339 of Amazing Spider-Man Vol. 1.
- The Sinister Six seen reflecting out of Spider-Man's eyes on the main image were from the cover of Amazing Spider-Man #337 by Erik J. Larsen.