History
The billboard for Mary Jane Watson's play The Importance of Being Earnest is on Bleecker Street, the location of Doctor Strange's 616 counterpart's Sanctum Sanctorum.
Later, the Daily Bugle publisher J. Jonah Jameson tasks Hoffman to come up with possible names for Otto Octavius, he suggests several names including Doctor Strange and Doctor Octopus. Jonah likes the name Doctor Strange, but says that it is already taken.[1]