Cadet Avery faced a field exam under Melinda May who later proved to be a real field action against a pack of cyberwolves sent by an unknown organization. Avery uses her technical experience using a controlled e.m.p. which disabled the cyberwolves.
During the Civil War caused by the Superhuman Registration Act, Bartles, a member of S.H.I.E.L.D., abused his power while attempting to arrest those who did not want to register. When he was about to shoot an already imprisoned boy, Officer Dobronski hit him, stunning him and freed the boys.
As he was about to execute the arrest, Charlie was convinced by General Ryker not to arrest him and told the other S.H.I.E.L.D. agents who were there with him that there had been a case of mistaken identity.
Agent Charles was a member of Gray Blade, the independent division of the S.H.I.E.L.D. specialized in performing international hostage rescues and intel gathering.
Charles informs Agent Mintz that the F.B.I. is still following some clues about Teresa Durand and is not agreeing with Mintz for insisting on using "deadly force".
Chelsea was a S.H.I.E.L.D. agent who expressed her disdain towards Victor von Doom when he was handed over to the agency by Ironheart, comparing him to Hitler and suggesting that putting him through the judicial process would be a waste of time and resources.
She rallied other two agents to Doom's cell, and attempted to convince the two guards, one of them being Todd, to abandon their positions. When the guards refused, Chelsea and the other two agents took them down and entered the cell. When they were getting ready to shoot Doom, Chelsea was taken over by Doom's mother Cynthia, who used her to shoot down the other two agents that had accompanied her. When Chelsea snapped out of it, Cynthia appeared and knocked her down before proceeding with her plan to break Victor out of the S.H.I.E.L.D. Helicarrier.
A S.H.I.E.L.D. Agent Class Five, Sergeant Davis was the leader of the commando unit stationed in Anchorage, Alaska.
As the Collective appeared and started rampaging in Alaska, he and his team of six men were sent to intercept him towards the Canadian border, having Hulkbuster Armors and a Nexus Nullifier ready for the confrontation, but they were all seemingly killed when the entity spotted them when they were at 22 miles behind him.
Doug and his partner were on guard at the Santa Monica Farmers' Market in Los Angeles when they noticed the presence of a person with probably super powers and tried to stop him but that person turned out to be the Flag-Smasher who seriously injured Doug.
Fritch is a former S.H.I.E.L.D. operative moved to the private sector and contacts Kyle Richmond to let him know that another former S.H.I.E.L.D. is passing sensitive information to an unidentified third group.
Honda was sent with Special Agents Minelli and Garrett to meet Ken Wind and offer him protection, but he firmly refused. As Garrett then rushed to rescue Elektra, Honda attempted to stop him, but Garrett fought him off.
Agent Keller was the head of the SHIELD Acquisition Department and explained to Pete Wisdom of Mys-Tech's involvement in the current events, and also called Col. Tigon Liger back into service.
After the battle with Mephisto ended, Keller accompanied Liger in search of the Kether Troop.
Lindsay thought that Iron Man was a showboat and that Dugan should had taken Fury's place as Director of S.H.I.E.L.D.
He had been in Thunderbolt's Hulkbusters for years, but when Hulk invaded Manhattan, he advised against any direct attack against him, hoping that he would just take revenge on his enemies and then leave.
Minelli was sent with Special Agents Honda and Garrett to meet Ken Wind and offer him protection, but he firmly refused. As Garrett then rushed to rescue Elektra, Minelli attempted to stop him, but she was eventually killed by Brad.
Agent Morgen was screening Elektra in the probe chamber, after she was caught in the San Conception base. Elektra then mind-controlled Garret to break her free, and Morgen was found dead as a result of a brain hemorrhage brought on by her psychic feedback.
Agent Rodriguez is an agent of S.H.I.E.L.D. part of the task force assigned with capturing the mutant terrorist Magneto. When Rodriguez was in high school, she had a mutant boyfriend with the ability to fly. Her boyfriend was beaten to death by a mutant hate group, causing Rodriguez to sympathise with Magneto's crusade of killing humans that would harm mutants. She leaked S.H.I.E.L.D. info to Magneto, and aided him in destroying S.H.I.E.L.D.'s Cerebro prototype.
Stassen fought Elektra when she broke into the San Conception base, nailing her with a taser, but before collapsing to the floor, she was still able to severely wound him by throwing her sword into his leg.
Todd was one of the two S.H.I.E.L.D. agents tasked with guarding Victor von Doom's cell aboard the Helicarrier. Todd and his fellow guard was approached by Chelsea and other two agents, who intended to kill Doom. When Chelsea failed to convince Todd and the other guard to abandon their positions, they were taken down by force before they could contact their superiors.
Tony was one of the agents assigned to watch over Tony Stark while he was hospitalized after the battle with his Life-Model Decoy, but he couldn't stop the Growing Man from capturing the multimillionaire industrialist.
Agent Travers was under the command of the Human Torch in charge of capturing the Squadron Supreme.
Together with another S.H.I.E.L.D. agent they found themselves on the scene of the battle between Power Princess and Warrior Woman with the intention of arresting Warrior Woman but instead they were both brutally killed with her swords.
Agent Whitaker was a rookie S.H.I.E.L.D. Agent who had recently transferred into New York and had been chosen for a covert operation to apprehend Venom by Nick Fury. The night before the operation, Whitaker and his team were partying at a dive bar, though Whitaker was reluctant to indulge until he spotted an attractive woman and was immediately infatuated with her. When the woman was sexually harassed by a group of men, Whitaker prepared to intercede, but the woman handily beat up the men herself before brazenly flirting with him. Whitaker accepted her offer of a one-night stand and they returned to his room, but the woman turned out to be the host of a clone of the Venom symbiote, killed him, and impersonated him the following day to infiltrate the mission.