- Super Hero Squad
- Squadron Supreme (Only appearance)
- Pocket Dimension
Thanos recruits Iron Man, Hulk, and the Scarlet Witch for a match against the Squadron Supreme of another dimension in a battle of heroes for the Grandmaster's Mind Gem.
- Title card's issue homage Avengers #70. The title is a variation on the idea that "those whom the gods would destroy, they first drive mad" (Quem Juppiter vult perdere, dementat prius - James Duport).