- Super Hero Squad
- S.H.I.E.L.D. Helicarrier
- Annihilus Ship
Thanos has the Space Gem stolen from him by his older sister Nebula. She uses the Squad Helicarrier's Teleporter to escape, but ends up in the Negative Zone. Wolverine and H.E.R.B.I.E. team up as they were the only ones aboard the Helicarrier at the time. Having just returned from a trip to Six Eggs Over Easy amusement park, Iron Man & Falcon venture into the Zone to save them.
- Title card's issue homage Fantastic Four #109
- The Iron Man from The Avengers: Earth's Mightiest Heroes (Animated Series) made a cameo appearance when Iron Man and Falcon travel to the Negative Zone.
- H.E.R.B.I.E. and Wolverine reference the myth that H.E.R.B.I.E was introduced because kids would mimic the Human Torch. H.E.R.B.I.E. dismissed the myth by saying kids are too smart to do such a reckless stunt.