Otto Octavius has conquered death! I am immortal! I am superior! Who can stand against me now? 
Appearing in 1st story
Featured Characters:
- ⏴ Superior Octopus / "Dr. Elliot Tolliver" (Otto Octavius) ⏵ (Main story and as Doctor Octopus in recap)
Supporting Characters:
- Horizon University
- Anna Maria Marconi (Main story and recap)
- Dr. Max Modell
- Numerous unnamed others
Antagonists:
- Night Shift (Reassembles)
- Digger (Roderick Krupp) (Returns; rejoins team)
- Dansen Macabre (Returns; rejoins team)
- Brothers Grimm (Percy & Barton Grimes) (Rejoin team)
- Skein (Sybil Dvorak) (Rejoins team)
- Waxman (Joins)
- Hydra
- Arnim Zola
- Gorgon ("Tomi Shishido") (First appearance; dies)
- Numerous unnamed agents
Other Characters:
- Numerous unnamed San Franciscans
- Count Nefaria (Luchino Nefaria) (Only on screen as a static image or video record)
- Master Pandemonium (Martin Preston) (Only on screen as a static image or video record)
- Graviton (Franklin Hall) (Only on screen as a static image or video record)
- Daredevil (Matt Murdock) (Referenced)
- Goliath (Billy Foster) (Referenced)
- Spider-Woman (Jess Drew) (Referenced)
- West Coast Avengers (Referenced)
- "Peter Parker" / Otto Octavius (Only in recap)
- TED Conferences LLC (Mentioned) (Topical Reference)
- Parker Industries (Mentioned)
- Peter Parker (Referenced)
- SFFD
- Dr. Faustus (Johann Fennhoff) (Mentioned)
- Thor (Odinson) (Referenced)
- High Council of Hydra (Mentioned)
- Gorgon (Tomi Shishido) (Mentioned)
- S.H.I.E.L.D. (Mentioned)
- Otto Octavius clones (First appearance)
- Miles Warren (Referenced)
- Inheritors (Referenced)
Races and Species:
- Humans (Main story and recap)
- Zombies
- Mutants
- Symbiotes (Mentioned)
- Octopuses (Mentioned)
- Gods (Referenced)
- Unicorns (Mentioned)
- LMDs (Mentioned)
Locations:
- Earth
- North America
- United States of America
- California
- San Francisco
- Bay Bridge
- The Auto Empire
- New York (Only in recap)
- New York City (Only in recap)
- Manhattan (Only in recap)
- Empire State University (Mentioned)
- Midtown (Only in recap)
- Parker Industries, New York Headquarters, 42nd Street (Mentioned)
- Chelsea (Only in recap)
- Pier 64 (Only in recap)
- Parker Industries (Only in recap)
- Pier 64 (Only in recap)
- Manhattan (Only in recap)
- New York City (Only in recap)
- California
- United States of America
- China (Mentioned)
- London, England, United Kingdom (Mentioned)
- Parker Industries, London Branch (Mentioned)
- North America
- Hell (Invoked)
Items:
- Superior Octopus' Suit and Tentacles
- Unstable Molecules (Mentioned)
- Octobots (Referenced)
- Arnim Zola's Robotic Body (Destruction)
Events:
- Secret Empire (Mentioned)
Synopsis for 1st story
- Synopsis not yet written
Appearing in "Check In"
Featured Characters:
- Web-Warriors (Main story and recap)
- ⏴ Spider-Woman (May Parker) ⏵ (Main story and recap)
- ⏴ Spider-UK (Billy Braddock) ⏵
- ⏴ Spider-Man (Pavitr Prabhakar)
- Spider-Ham (Peter Porker) ⏵ (Main story and recap)
- ⏴ Spider-Man (Hobie Brown) ⏵ (Main story and recap)
- Spider-Gwen (Gwen Stacy) (Main story and recap)
- Doctor Octopus (Octavia Otto) ⏵ (Main story and recap)
- The Spider-Man (Peter Parker) (Only in recap)
Supporting Characters:
Antagonists:
- Thunderstrike (Eric Masters) ⏵ (First appearance chronologically)
- Inheritors
Other Characters:
- Red Skull (Johann Shmidt) (Mentioned)
- Captain Britain Corps (Mentioned)
- Superior Octopus (Otto Octavius) (Mentioned)
- Numerous unidentified Spider-Bots (Destroyed)
Races and Species:
- Humans (Main story and recap)
- Pig-Spider Hybrids (Main story and recap)
- Robots
Locations:
- Earth-001 (Main story and recap)
- The Great Hall
- Loomworld (Mentioned) (Destroyed)
- Earth-138
- Earth
- United States of America
- New York
- New York City
- Manhattan (First appearance chronologically)
- Lower East Side (First appearance chronologically)
- Bowery (First appearance chronologically)
- Lower East Side (First appearance chronologically)
- Manhattan (First appearance chronologically)
- New York City
- New York
- United States of America
- Earth
- Earth-833 (Mentioned) (Destroyed)
- Earth-3145
- Prime Marvel Universe (Only on screen as a static image or video record)
- Earth (Only on screen as a static image or video record)
Items:
- Spider-Woman's Suit (Main story and recap)
- Web-Shooters (Main story and recap)
- Spider-Men's Suits (Main story and recap)
- Web of Life and Destiny
- Thunderstrike (First appearance)
- Venom Symbiote
- Doctor Octopus' Tentacles (Main story and recap)
- Dimensional Travel Watch
Synopsis for "Check In"
- Synopsis not yet written
Solicit Synopsis
DOC OCK-TOBER STARTS HERE IN THIS SPIDER-GEDDON TIE IN!
• Doc Ock has set up shop as San Francisco’s protector, but you won’t believe his methods.
• Some of Otto Octavius’s new super hero strategies may make Spider-Man regret letting him free, but the good doctor swears that he’s the SUPERIOR OCTOPUS!
• Chistos Gage (AMAZING SPIDER-MAN) and Mike Hawthorne (Deadpool) will change the way you look at super hero comics.