Trouble is a five-issue romance comic book limited series published by Marvel Comics under its Epic line in 2003. Written by Mark Millar and illustrated by Terry and Rachel Dodson the series deals with teen pregnancy. The basic concept was created by Bill Jemas and Joe Quesada.
Trouble was originally considered by Marvel's editorial group as the possible origin of Spider-Man, but after the book was not received very well by many comic book fans the story was declared not "official" Marvel continuity. It was also meant to re-popularize romance comics (which were very popular in the 1950s, selling millions of copies), but failed.
A trade paperback collecting the five issues was originally scheduled to be published on February 18th 2004, but canceled when Epic was shut down after Bill Jemas, who had been a driving force behind the imprint, resigned as president of Marvel Comics.
The series' main characters, May, Ben, Mary and Richard, were obviously meant to be Peter Parker's Aunt May and Uncle Ben along with his parents Richard and Mary Parker. Thus, the revelation that Aunt May is actually Peter Parker's mother was highly controversial among Spider-Man fans. May's behavior in Trouble did not match Aunt May's character, nor did the characters' appearances match their the corresponding characters' looks in previous Spider-Man comics. Enough of the early lives of Spider-Man's family been established previously that the story contradicted prior continuity. For example, Aunt May and Uncle Ben were much older than Spider-Man's parents, and his parents met while working for the C.I.A. Aunt May was also established as never having had a child. Complaints from fans were so strong that Marvel later declared that the story was not part of the "official" Marvel continuity.
And while Dodson's art was well liked, Millar's dialogue in Trouble was criticized as not representative of the time it is set in (supposedly the 1970s)  and his storytelling failed to grab the audience, with many complaining that the characters were written too similar and hard to keep apart; "Save for the fact that one of the girls will do it on the first date when the other one won't". 
- Lee, Stan (w), Lieber, Larry (p), Demeo, Mickey (i). "The Parents of Peter Parker!" Amazing Spider-Man Annual v1 #5 1965 Marvel Comics (11/2).
- Stern, Roger (w), Romita, John (p), Milgrom, Al (i). "The Amazing Parkers" Untold Tales of Spider-Man Flashback v1 #-1 (Minus 1) July, 1997 Marvel Comics (8/4).
- Review of Trouble #1 by Chris Allen on moviepoopshoot.com
- Review of Trouble #1 by Paul O'Brien on The X-Axis, 13 July 2003
- SpiderFan.org Top Ten Reasons Not To Take The Trouble Mini-series Seriously