Why can't a couple of regular non-super heroes just decide to stone-cold kick it with Sergei Kravinoff? 
Appearing in 1st story
Featured Characters:
- Squirrel Girl / Lady Crimepocalypse (Doreen Green) (Main story and recap) (First appearance as Lady Crimepocalypse) (Joins the Justice Pals)
Supporting Characters:
- Justice Pals (First appearance)
- Nautical Nancy (Nancy Whitehead) (Main story and recap) (First appearance as Nautical Nancy) (Joins)
- Zorro 2: Better Than Zorro (Tomas Lara-Perez) (First appearance as Zorro 2: Better Than Zorro) (Joins)
- Super-Powers Woman (Mary) (First appearance as Super-Powers Woman) (Joins)
- Brain Drain / "Brian Drayne" / Doctor Musclefists (Werner Schmidt) (First appearance as Doctor Musclefists) (Joins)
- Captain Crimehater (Ken Shiga) (First appearance as Captain Crimehater) (Joins)
- Kraven the Hunter / The Hunter (Sergei Kravinoff) (Main story and recap) (First appearance as The Hunter) (Joins)
- Tippy-Toe
Antagonists:
- Unnamed poachers (First appearance)
- Escape room proprietor
Other Characters:
- Jorge Louis Borges (Mentioned) (Topical Reference)
- Peter Parker (Earth-616)
- Doreen's students
- Ember Quade
- Danilo Chua (Unnamed)
- Kamala Khan
- Numerous unnamed others
- Iron Man (Tony Stark) (Mentioned)
- Melissa Morbeck (Mentioned)
- Ratatoskr (Mentioned)
- Kara Palamas (Named only) (Only on screen as a static image or video record)
- Shannon Sugarbaker (Mentioned)
- Mew
- God (Yahweh) (Invoked)
- Namor (Poster)
- Doctor Doom (Victor von Doom) (Mentioned)
- Ultron Dinosaur (Only in recap)
- Howard the Duck
- Howard T. Duck Private Investigations (Mentioned)
- Biggs (Mentioned)
- Justice League (Mentioned) (Topical Reference)
- Zorro (Don Diego de la Vega) (Mentioned) (Topical Reference)
- Captain Amazo (Mentioned)
Races and Species:
- Humans (Main story and recap)
- Human-Inhuman Hybrids
- Cats
- Squirrels
- Cyborgs
- Atlantean-Human Hybrids (Poster)
- Jaguars
- Amazons of Themiscira (Mentioned) (Topical Reference)
- Dinosaurs (Mentioned)
- Robots (Only in recap)
- Lions (Mentioned)
- Duckworldians
Locations:
- The Library of Babel (Illusion or holographic simulation) (Topical Reference)
- Prime Marvel Universe (Main story and recap)
- Earth (Main story and recap)
- North America
- United States of America
- New York
- New York City
- Manhattan
- East Village
- Greenwich Village
- Doreen and Nancy's apartment
- John F. Kennedy International Airport, Jamaica, Queens (Mentioned)
- Manhattan
- New York City
- New York
- United States of America
- South America
- Antarctica (Only in recap)
- Palmer Peninsula (Only in recap)
- Savage Land (Only in recap)
- The Core (Mount Flavius) (Only in recap)
- Savage Land (Only in recap)
- Palmer Peninsula (Only in recap)
- North America
- Earth (Main story and recap)
- Earth-18779 (Escape Room Scenario)
Items:
- Squirrel Girl's Costume
- Spider-Man's Suit
- Squirrel Girl's zine (Mentioned)
- Trident of Neptune (Poster)
- Kraven's Lion's Head Vest
- Lasso of Truth (Mentioned) (Topical Reference)
Vehicles:
Events:
- Animal House (Mentioned)
Synopsis for 1st story
- Synopsis not yet written
Solicit Synopsis
• Doreen Green (A.K.A. the super hero Squirrel Girl) and her friend Nancy Whitehead (an unrelated civilian) have had a great idea: Let’s get some friends together and play an escape room! Escape rooms are those real-life games where you get locked in a room and have an hour to escape before you die!
• In the game, I mean. It’s not like if you die in the game you die in real life! Hah hah.
• They gather KOI BOI, CHIPMUNK HUNK, BRAIN DRAIN and, as a special guest... their good friend KRAVEN THE HUNTER.
• BUT WHEN THEY ENTER THE ROOM IT TURNS OUT THAT IF YOU DIE IN THE GAME YOU DIE IN REAL LIFE!! TWIST!!
• It’s everything you crave: friendship, adventure and a room full of death traps that you can only find in SQUIRREL GIRL!Trivia
- Doreen's reveal of her identity to Kraven, namely the panel in which she proclaims "My name is Doreen Green, and I've been the Unbeatable Squirrel Girl since I was ten years old," is a homage to Spider-Man's unmasking in Civil War #2.